Degradation and utilisation of chondroitin sulphate by Streptococcus intermedius
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چکیده
منابع مشابه
Degradation of Intravenously Injected Chondroitin 4-Sulphate in the Rat
The degradation of chondroitin 4-[35S]sulphate isolated from chick-embryo cartilage was studied in the rat by experiments on free-range animals, on wholly anaesthetized animals with ureter cannulae, by perfusion of isolated liver, by whole-body radioautography and by isolation of liver lysosomes. After injection into rats 68% of the radioactivity was recovered in the urine after 24h, approximat...
متن کاملThe degradation of cartilage chondroitin sulphate by the chondroitinase of Proteus vulgaris.
Specificity. Pyruvate is reduced at less than 2 % of the rate of an equimolar amount of hydroxypyruvate by this preparation of the enzyme. Since both pyruvate and hydroxypyruvate rapidly oxidize DPNH in the presence of lactic dehydrogenase of muscle, which is obtainable commercially (Boehringer und Soehne, Mannheim), a differential analysis of pyruvate and hydroxypyruvate in mixtures of the two...
متن کاملNature of the interaction of chondroitin 4-sulphate and chondroitin sulphate-proteoglycan with collagen.
The electrostatic interaction of chondroitin sulphate and the chondroitin sulphate-proteoglycan with collagen was studied by chromatography of the glycosaminoglycan and the proteoglycan on a collagen gel. The observed binding between the macromolecules increased with decreasing pH and ionic strength, and was significant under physiological conditions. A study of the interaction between chondroi...
متن کاملZonal distribution of chondroitin-4-sulphate/dermatan sulphate and chondroitin-6-sulphate in normal and diseased human synovium.
OBJECTIVES Chondroitin sulphate is the major sulphated glycosaminoglycan present in the extracellular matrix of soft connective tissues and the aim of this study was to investigate the distribution of chondroitin sulphate species in normal and diseased synovium. METHODS Distribution of chondroitin-4-sulphate/dermatan sulphate (Ch4S/DS) and chondroitin-6-sulphate in normal (n = 6), osteoarthri...
متن کاملChondroitin sulphate and keratan sulphate are almost isosteric.
Keratan sulphate and chondroitin sulphate (KS and CS) in the 2-fold helical configurations that are prevalent in solution are of very similar tacticity. The chiral centres, anionic sites and hydrophobic patches are in identical conformations. Only the position of the acetamido group varies from CS to KS, but part of its intramolecular H-bonding potential in CS is retained in KS. The formation o...
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ژورنال
عنوان ژورنال: Journal of Medical Microbiology
سال: 1996
ISSN: 0022-2615,1473-5644
DOI: 10.1099/00222615-44-5-372